Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 8/20 | 0.49 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | GPR52 | Q9Y2T5 | 3/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CDK3 | Q00526 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | GRK2 | P25098 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5314803 | 0.91 | LCK (0.40) | LCKKDRGPR52ROCK1ALDH1A1 | |
| SCHEMBL5314681 | 0.91 | LCK (0.41) | LCKKDRGPR52ROCK1ROCK2 | |
| SCHEMBL5316017 | 0.84 | KDR (0.51) | LCKKDR | |
| SCHEMBL5314751 | 0.83 | LCK (0.50) | LCKKDR | |
| SCHEMBL5313953 | 0.83 | KDR (0.51) | LCKKDRGPR52ROCK2GRK2 | |
| SCHEMBL5314211 | 0.82 | HDAC1 (0.41) | LCKKDRALDH1A1ROCK2GRK2 | |
| SCHEMBL5315254 | 0.79 | MAPT (0.42) | LCKKDRALDH1A1 | |
| SCHEMBL5312793 | 0.78 | LCK (0.38) | LCKALDH1A1CCNE1CDK2CDK3 | |
| SCHEMBL5315698 | 0.78 | LCK (0.38) | LCKALDH1A1ROCK2 | |
| SCHEMBL5314682 | 0.75 | LCK (0.43) | LCKKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | claimed |
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |