Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 17/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 12/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5316545 | 0.84 | OPRD1 (0.68) | OPRD1KCNH2 | |
| SCHEMBL5314997 | 0.83 | OPRD1 (0.81) | OPRD1KCNH2 | |
| SCHEMBL5313435 | 0.81 | OPRD1 (0.83) | OPRD1KCNH2 | |
| SCHEMBL14529821 | 0.80 | OPRD1 (0.70) | OPRD1KCNH2 | |
| SCHEMBL5314036 | 0.77 | OPRD1 (0.70) | OPRD1KCNH2 | |
| SCHEMBL5316799 | 0.77 | OPRD1 (1.00) | OPRD1KCNH2 | |
| SCHEMBL5312960 | 0.77 | OPRD1 (1.00) | OPRD1KCNH2 | |
| SCHEMBL5314784 | 0.77 | OPRD1 (1.00) | OPRD1KCNH2 | |
| SCHEMBL14530107 | 0.77 | OPRD1 (0.76) | OPRD1KCNH2 | |
| SCHEMBL5313541 | 0.77 | OPRD1 (0.67) | OPRD1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007057775-A1 | SPIROPIPERIDINE DERIVATIVES | PFIZER LIMITED (GB) | 2007-05-24 | — | — | WO | disclosed |