Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 16/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 6/20 | 0.38 |
| ▸ | GNRHR | P30968 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5307649 | 0.92 | CASR (0.43) | CASR | |
| SCHEMBL5308905 | 0.90 | GNRHR (0.35) | CASRGNRHR | |
| SCHEMBL5310889 | 0.87 | MAOB (0.35) | CASRGNRHR | |
| SCHEMBL5307986 | 0.81 | CASR (0.45) | CASRNR1I2GNRHR | |
| SCHEMBL5311948 | 0.79 | CASR (0.43) | CASR | |
| SCHEMBL5311952 | 0.76 | GNRHR (0.37) | CASRGNRHR | |
| SCHEMBL5310667 | 0.73 | CASR (0.42) | CASR | |
| SCHEMBL5308386 | 0.73 | CASR (0.54) | CASR | |
| SCHEMBL5313085 | 0.72 | CASR (0.51) | CASRGNRHR | |
| SCHEMBL5314824 | 0.71 | CASR (0.38) | CASRNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007044796-A2 | PYRIDAZINONE COMPOUNDS AS CALCILYTICS | NPS PHARMACEUTICALS, INC. (US) | 2007-04-19 | — | — | WO | claimed |
| WO-2007044796-A2 | PYRIDAZINONE COMPOUNDS AS CALCILYTICS | NPS PHARMACEUTICALS, INC. (US) | 2007-04-19 | — | — | WO | disclosed |