Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | CASR | P41180 | 4/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.33 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.33 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | GNRHR | P30968 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5307649 | 0.89 | CASR (0.43) | CASRALDH1A1ALDH1A3 | |
| SCHEMBL5308905 | 0.88 | GNRHR (0.35) | CASRALDH1A1ALDH1A3GNRHR | |
| SCHEMBL5314826 | 0.87 | CASR (0.41) | CASRGNRHR | |
| SCHEMBL5310704 | 0.82 | CASR (0.40) | MAOBCASRMAPK14ALDH1A1ALDH1A2 | |
| SCHEMBL5311952 | 0.80 | GNRHR (0.37) | CASRGNRHRTP53GRIN1GRIN2B | |
| SCHEMBL5311948 | 0.75 | CASR (0.43) | CASRALDH1A1ALDH1A3 | |
| SCHEMBL5311895 | 0.74 | GNRHR (0.42) | CASRGNRHRL3MBTL1 | |
| SCHEMBL5310887 | 0.74 | LMNA (0.38) | MAOBCASRMAPK14ALDH1A1SGMS2 | |
| SCHEMBL5308221 | 0.73 | ALDH1A1 (0.42) | MAOBCASRMAPK14ALDH1A1MEN1 | |
| SCHEMBL5313082 | 0.73 | LMNA (0.45) | MAOBCASRMAPK14ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007044796-A2 | PYRIDAZINONE COMPOUNDS AS CALCILYTICS | NPS PHARMACEUTICALS, INC. (US) | 2007-04-19 | — | — | WO | disclosed |