Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5314851 | 0.95 | POLB (0.53) | POLBHPGDKMT2AHTTUSP2 | |
| SCHEMBL5316192 | 0.95 | HTT (0.52) | POLBHPGDKMT2AHTTUSP2 | |
| SCHEMBL5316551 | 0.93 | POLB (0.48) | POLBHPGDKMT2AHTTUSP2 | |
| SCHEMBL5319733 | 0.93 | POLB (0.48) | POLBHPGDKMT2AHTTUSP2 | |
| SCHEMBL5318143 | 0.93 | POLB (0.50) | POLBHPGDKMT2AHTTUSP2 | |
| SCHEMBL5318355 | 0.91 | POLB (0.60) | POLBHPGDKMT2ATSHRALDH1A1 | |
| SCHEMBL5318125 | 0.91 | POLB (0.49) | POLBHPGDKMT2AHTTUSP2 | |
| SCHEMBL5315856 | 0.91 | POLB (0.49) | POLBHPGDKMT2AHTTUSP2 | |
| SCHEMBL5314736 | 0.90 | KMT2A (0.50) | POLBKMT2ASMN1; SMN2HTR1ADRD2 | |
| SCHEMBL5314521 | 0.90 | POLB (0.46) | POLBHPGDKMT2AHTTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007069986-A1 | NEW OXABISPIDINE COMPOUNDS FOR THE TREATMENT OF CARDIAC ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2007-06-21 | — | — | WO | claimed |