Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.51 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.51 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.51 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.51 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18816708 | 0.87 | PLAU (0.54) | L3MBTL1MAPTTP53ALDH1A1HSD17B1 | |
| SCHEMBL18816702 | 0.84 | POLB (0.53) | L3MBTL1MAPTHSD17B1HSD17B2TSHR | |
| SCHEMBL529916 | 0.83 | POLB (0.60) | L3MBTL1HTTTP53RAB9AKDM4E | |
| SCHEMBL28001824 | 0.81 | HSP90AA1 (0.57) | L3MBTL1MAPTHTTNPSR1ALDH1A1 | |
| SCHEMBL7511970 | 0.81 | MAPT (0.62) | MAPTHTTNPSR1TP53ALDH1A1 | |
| SCHEMBL18816716 | 0.79 | PLAU (0.67) | L3MBTL1MAPTTP53ALDH1A1HSP90AA1 | |
| SCHEMBL4833864 | 0.78 | MAPT (0.58) | MAPTHTTNPSR1ALDH1A1TSHR | |
| SCHEMBL13850379 | 0.78 | L3MBTL1 (0.53) | L3MBTL1MAPTHTTNPSR1ALDH1A1 | |
| SCHEMBL529976 | 0.76 | KDM4E (0.71) | HTTNPSR1ALDH1A1HSD17B1HSD17B2 | |
| SCHEMBL5231122 | 0.76 | KMT2A (0.61) | L3MBTL1MAPTHTTNPSR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | claimed |