Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 3/20 | 0.36 |
| ▸ | ACACA | Q13085 | 2/20 | 0.36 |
| ▸ | F2R | P25116 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4127041 | 0.94 | HTR2C (0.56) | HTR2CHTR2AHTR2BCTSBCTSS | |
| SCHEMBL4127039 | 0.94 | HTR2C (0.56) | HTR2CHTR2AHTR2BCTSBCTSS | |
| SCHEMBL5315275 | 0.91 | HTR2C (0.50) | HTR2CHTR2AHTR2BCTSBCTSS | |
| SCHEMBL4126436 | 0.89 | HTR2A (0.51) | HTR2CHTR2AHTR2BCTSBCTSS | |
| SCHEMBL4126434 | 0.89 | HTR2A (0.51) | HTR2CHTR2AHTR2BCTSBCTSS | |
| SCHEMBL5315744 | 0.88 | HTR2C (0.42) | HTR2CHTR2AHTR2BCTSBCTSS | |
| SCHEMBL5315451 | 0.85 | HTR2C (0.40) | HTR2CHTR2AHTR2BSLC6A4SLC6A3 | |
| SCHEMBL4138979 | 0.84 | HTR2C (0.43) | HTR2CHTR2AHTR2BACACBACACA | |
| SCHEMBL4138978 | 0.84 | HTR2C (0.43) | HTR2CHTR2AHTR2BACACBACACA | |
| SCHEMBL4129089 | 0.84 | HTR2C (0.56) | HTR2CHTR2AHTR2BACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025144-A1 | 5-HT2C RECEPTOR AGONISTS AS ANORECTIC AGENTS | UNIVERSITY OF ILLINOIS - CHICAGO (US) | 2007-03-01 | — | — | WO | disclosed |