Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | HTR2B | P41595 | 3/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 4/20 | 0.36 |
| ▸ | ACACA | Q13085 | 3/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4129039 | 0.94 | HTR2C (0.46) | HTR2CHTR2AHTR2BCNR1DRD2 | |
| SCHEMBL4129040 | 0.94 | HTR2C (0.46) | HTR2CHTR2AHTR2BCNR1DRD2 | |
| SCHEMBL5315275 | 0.93 | HTR2C (0.50) | HTR2CHTR2AHTR2BCNR1DRD2 | |
| SCHEMBL4126434 | 0.90 | HTR2A (0.51) | HTR2CHTR2AHTR2BCNR1DRD2 | |
| SCHEMBL4126436 | 0.90 | HTR2A (0.51) | HTR2CHTR2AHTR2BCNR1DRD2 | |
| SCHEMBL5315446 | 0.88 | DRD2 (0.40) | HTR2CHTR2AHTR2BCNR1DRD2 | |
| SCHEMBL5315320 | 0.88 | HTR2C (0.50) | HTR2CHTR2AHTR2BCTSBCTSS | |
| SCHEMBL4129089 | 0.87 | HTR2C (0.56) | HTR2CHTR2AHTR2BCNR1DRD2 | |
| SCHEMBL4129091 | 0.87 | HTR2C (0.56) | HTR2CHTR2AHTR2BCNR1DRD2 | |
| SCHEMBL4134708 | 0.81 | DRD2 (0.43) | HTR2CCNR1DRD2KDM4EACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025144-A1 | 5-HT2C RECEPTOR AGONISTS AS ANORECTIC AGENTS | UNIVERSITY OF ILLINOIS - CHICAGO (US) | 2007-03-01 | — | — | WO | disclosed |