Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 14/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | PTGES | O14684 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3851328 | 0.93 | TAS2R14 (0.59) | TAS2R14MAPK1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL13714165 | 0.93 | TAS2R14 (0.59) | TAS2R14MAPK1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3856007 | 0.92 | MAPK1 (0.52) | TAS2R14MAPK1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3852268 | 0.89 | PTGES (0.61) | TAS2R14PTGESMEN1KMT2ALMNA | |
| SCHEMBL5311979 | 0.86 | PTGES (0.69) | TAS2R14PTGESMEN1KMT2ALMNA | |
| SCHEMBL13714179 | 0.84 | TAS2R14 (0.59) | TAS2R14MEN1KMT2A | |
| SCHEMBL3853015 | 0.83 | TAS2R14 (0.72) | TAS2R14MAPK1MEN1KMT2ALMNA | |
| SCHEMBL3856384 | 0.82 | TAS2R14 (0.56) | TAS2R14MAPK1PTGESLMNA | |
| SCHEMBL3858876 | 0.82 | TAS2R14 (0.55) | TAS2R14MEN1KMT2A | |
| SCHEMBL3853063 | 0.81 | TAS2R14 (0.76) | TAS2R14MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007067817-A1 | ABCA1 ELEVATING COMPOUNDS | CV THERAPEUTICS, INC. (US) | 2007-06-14 | — | — | WO | disclosed |