SCHEMBL5315495

SCHEMBL5315495

O=C(O)c1ccc(N(C(=O)NCl)c2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.46
MEN1 O00255 2/20 0.46
NPSR1 Q6W5P4 2/20 0.45
TSHR P16473 3/20 0.45
DAO P14920 1/20 0.45
NAPRT Q6XQN6 1/20 0.45
APAF1 O14727 1/20 0.44
TDP2 O95551 1/20 0.44
NSD2 O96028 1/20 0.44
CASP3 P42574 1/20 0.44
CACNA1B Q00975 1/20 0.44
APBA1 Q02410 1/20 0.44
HKDC1 Q2TB90 1/20 0.44
SENP8 Q96LD8 1/20 0.44
SENP7 Q9BQF6 1/20 0.44
SENP6 Q9GZR1 1/20 0.44
APOBEC3G Q9HC16 1/20 0.44
SAE1 Q9UBE0 1/20 0.44
UBA2 Q9UBT2 1/20 0.44
SRD5A2 P31213 4/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4359334 0.89 NPSR1 (0.56) KMT2AMEN1NPSR1ALDH1A1NPC1
Hydrochloric Acid SCHEMBL27946914 0.87 NPSR1 (0.54) KMT2AMEN1NPSR1ALDH1A1NPC1
SCHEMBL6243853 0.76 PTGIR (0.50) KMT2AMEN1NPSR1CACNA1BALDH1A1
SCHEMBL1304443 0.76 TSHR (0.50) KMT2AMEN1NPSR1TSHRDAO
SCHEMBL2793365 0.75 ALDH1A1 (0.44) KMT2AMEN1NPSR1TSHRCES2
SCHEMBL2850194 0.75 NPSR1 (0.44) KMT2AMEN1NPSR1TSHRNAPRT
SCHEMBL2596293 0.74 TSHR (0.59) KMT2AMEN1NPSR1TSHRDAO
SCHEMBL1246652 0.74 TSHR (0.59) KMT2AMEN1NPSR1TSHRDAO
SCHEMBL10335782 0.73 PPARA (0.54) KMT2AMEN1TSHRALDH1A1POLB
SCHEMBL10777656 0.73 TSHR (0.41) KMT2AMEN1TSHRCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007044309-A2 DEVICE AND METHOD FOR INHIBITING AGE COMPLEX FORMATION VASIX CORPORATION (US) 2007-04-19 WO disclosed