Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.48 |
| ▸ | CA1 | P00915 | 5/20 | 0.48 |
| ▸ | CA9 | Q16790 | 5/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28929084 | 0.88 | ALDH1A1 (0.48) | CA12CA1CA9CA2ALDH1A1 | |
| SCHEMBL5695010 | 0.87 | CA12 (0.61) | CA12CA1CA9CA2ALDH1A1 | |
| SCHEMBL27866693 | 0.87 | CA12 (0.61) | CA12CA1CA9CA2ALDH1A1 | |
| SCHEMBL5695101 | 0.87 | CA12 (0.61) | CA12CA1CA9CA2ALDH1A1 | |
| SCHEMBL9665534 | 0.87 | CA12 (0.61) | CA12CA1CA9CA2ALDH1A1 | |
| SCHEMBL635408 | 0.87 | CA12 (0.61) | CA12CA1CA9CA2ALDH1A1 | |
| SCHEMBL11387308 | 0.87 | CA12 (0.61) | CA12CA1CA9CA2ALDH1A1 | |
| SCHEMBL17956778 | 0.87 | CA12 (0.61) | CA12CA1CA9CA2ALDH1A1 | |
| SCHEMBL15420 | 0.87 | ALDH1A1 (0.56) | CA12CA1CA9CA2ALDH1A1 | |
| SCHEMBL28483475 | 0.85 | ALDH1A1 (0.54) | CA12CA1CA9CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1610126-B1 | A system for determining the electrical potential across a membrane | UNIV CALIFORNIA (US) | 2014-04-30 | — | — | EP | disclosed |
| EP-1409456-B1 | DETECTION OF TRANSMEMBRANE POTENTIALS BY OPTICAL METHODS | UNIV CALIFORNIA (US) | 2012-02-08 | — | — | EP | disclosed |
| EP-0977035-B2 | A system for determining the electrical potential across a membrane | UNIV CALIFORNIA (US) | 2010-07-21 | — | — | EP | disclosed |
| US-7687282-B2 | Detection of transmembrane potentials by optical methods | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-03-30 | — | — | US | disclosed |
| US-7173130-B2 | Detection of transmembrane potentials by optical methods | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-02-06 | — | — | US | disclosed |
| US-20070026384-A1 | Detection of transmembrane potentials by optical methods | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-02-01 | — | — | US | disclosed |
| US-7118899-B2 | Detection of transmembrane potentials by optical methods | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-10-10 | — | — | US | disclosed |
| US-7115401-B2 | Detection of transmembrane potentials by optical methods | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-10-03 | — | — | US | disclosed |
| US-7087416-B2 | Detection of transmembrane potentials by optical methods | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-08-08 | — | — | US | disclosed |
| EP-1610126-A1 | A system for determining the electrical potential across a membrane | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-12-28 | — | — | EP | disclosed |
| US-20030129670-A1 | Detection of transmembrane potentials by optical methods | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-07-10 | — | — | US | disclosed |
| US-20020164577-A1 | Detection of transmembrane potentials by optical methods | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-11-07 | — | — | US | disclosed |
| US-20020137201-A1 | DETECTION OF TRANSMEMBRANE POTENTIALS BY OPTICAL METHODS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-09-26 | — | — | US | disclosed |
| US-6342379-B1 | Detection of transmembrane potentials by optical methods | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-01-29 | — | — | US | disclosed |
| WO-2001042211-A2 | DETECTION OF TRANSMEMBRANE POTENTIALS BY OPTICAL METHODS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2001-06-14 | — | — | WO | disclosed |
| US-6107066-A | Detection of transmembrane potentials by optical methods | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-08-22 | — | — | US | disclosed |
| EP-0977035-A2 | A system for determining the electrical potential across a membrane | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-02-02 | — | — | EP | disclosed |
| EP-0834074-B1 | DETECTION OF TRANSMEMBRANE POTENTIALS BY OPTICAL METHODS | UNIV CALIFORNIA (US) | 1999-11-03 | — | — | EP | disclosed |
| EP-0834074-A1 | DETECTION OF TRANSMEMBRANE POTENTIALS BY OPTICAL METHODS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-04-08 | — | — | EP | disclosed |
| WO-1996041166-A2 | DETECTION OF TRANSMEMBRANE POTENTIALS BY OPTICAL METHODS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070026384-A1 | Detection of transmembrane potentials by optical methods | MBOAT1, TRPM4, NME4 | CA12 909/4885CA1 1244/4885CA9 2105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.