Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | TYK2 | P29597 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.42 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.42 |
| ▸ | ITGAL | P20701 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6989227 | 0.89 | RAB9A (0.43) | RAB9ANPC1KMT2ACES2CES1 | |
| SCHEMBL6989488 | 0.80 | RAB9A (0.42) | RAB9ANPC1KMT2AMEN1CES2 | |
| SCHEMBL13226271 | 0.79 | RAB9A (0.57) | RAB9ANPC1KMT2AMEN1CES2 | |
| SCHEMBL2204173 | 0.78 | NPC1 (0.57) | RAB9ANPC1KMT2AMEN1CES2 | |
| SCHEMBL5313994 | 0.77 | NPC1 (0.59) | RAB9ANPC1KMT2AMEN1CES2 | |
| SCHEMBL1127907 | 0.77 | CES2 (0.56) | RAB9ANPC1KMT2AMEN1CES2 | |
| SCHEMBL30739660 | 0.76 | NPC1 (0.63) | RAB9ANPC1KMT2AMEN1CES2 | |
| SCHEMBL9363197 | 0.76 | KMT2A (0.57) | RAB9ANPC1KMT2AMEN1CES2 | |
| SCHEMBL13527491 | 0.76 | RAB9A (0.53) | RAB9ANPC1KMT2AMEN1CES2 | |
| SCHEMBL19523055 | 0.75 | RAB9A (0.53) | RAB9ANPC1KMT2AMEN1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007066496-A1 | BENZOYLUREA COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-14 | — | — | WO | disclosed |
| WO-2007066496-A1 | BENZOYLUREA COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-14 | — | — | WO | disclosed |