Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 11/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 11/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 11/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 11/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 11/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 11/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5156572 | 0.87 | MRGPRX4 (0.46) | MRGPRX4PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5152540 | 0.82 | PSEN1 (0.46) | MRGPRX4PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5151311 | 0.81 | MRGPRX4 (0.47) | MRGPRX4PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5149581 | 0.80 | MRGPRX4 (0.46) | MRGPRX4PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5156703 | 0.77 | FABP4 (0.54) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL5156096 | 0.76 | PSEN1 (0.45) | MRGPRX4PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5151495 | 0.75 | PPARG (0.44) | MRGPRX4PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5315810 | 0.74 | PSEN1 (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL5152291 | 0.73 | MAOB (0.54) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL5319394 | 0.72 | KMT2A (0.38) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007071456-A1 | FLUORENES AND CARBAZOLES AS LIGANDS OF THE EP2 RECEPTOR | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-06-28 | — | — | WO | disclosed |