Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 12/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 8/20 | 0.48 |
| ▸ | ABCC1 | P33527 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14103784 | 0.73 | MAPT (0.47) | ABCG2ABCB1ABCC1MAPTTP53 | |
| SCHEMBL14103870 | 0.72 | MAPT (0.46) | ABCG2ABCB1ABCC1MAPTTP53 | |
| SCHEMBL5316009 | 0.72 | MAPT (0.62) | ABCG2ABCB1ABCC1HTTMAPT | |
| SCHEMBL7616076 | 0.71 | ALDH1A1 (0.58) | ABCG2HTTMAPTSMN1; SMN2KMT2A | |
| SCHEMBL21099859 | 0.69 | HTT (0.63) | HTTKMT2APDE4APDE4BPDE4C | |
| SCHEMBL10268901 | 0.69 | HTT (0.63) | HTTSMN1; SMN2KMT2APDE4APDE4B | |
| SCHEMBL24174509 | 0.67 | HTT (0.61) | HTTKMT2APDE4APDE4BPDE4C | |
| SCHEMBL30748848 | 0.67 | HTT (0.61) | HTTKMT2APDE4APDE4BPDE4C | |
| SCHEMBL5329628 | 0.66 | MEN1 (0.65) | ABCG2MAPTTP53SMN1; SMN2KMT2A | |
| SCHEMBL13840493 | 0.65 | HTT (0.58) | HTTKMT2APDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056214-A2 | N-ALKYL-N-ARYL-THIENOPYRIMIDIN-R-AMINES AND USES THEREOF | CYTOVIA, INC (US) | 2007-05-18 | — | — | WO | claimed |