Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 4/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5315884 | 0.96 | TRPM8 (0.53) | TRPM8TSHRPPARAALDH1A1KDM4E | |
| SCHEMBL14464512 | 0.95 | TRPM8 (0.52) | TRPM8TSHRPPARAALDH1A1KDM4E | |
| SCHEMBL5315896 | 0.92 | TRPM8 (0.60) | TRPM8TSHRALDH1A1RAB9AMEN1 | |
| SCHEMBL5316415 | 0.91 | TSHR (0.49) | TRPM8TSHRPPARAALDH1A1KDM4E | |
| SCHEMBL14463955 | 0.90 | TRPM8 (0.54) | TRPM8TSHRALDH1A1KDM4ERAB9A | |
| SCHEMBL14464531 | 0.89 | TRPM8 (0.53) | TRPM8TSHRPPARAALDH1A1KDM4E | |
| SCHEMBL5321993 | 0.88 | TRPM8 (0.67) | TRPM8TSHRKDM4ERAB9ANPC1 | |
| SCHEMBL5318380 | 0.88 | TRPM8 (0.52) | TRPM8ALDH1A1KDM4ERAB9ANPC1 | |
| Trifluoroacetic Acid SCHEMBL5320030 | 0.88 | TRPM8 (0.56) | TRPM8TSHRALDH1A1RAB9AMEN1 | |
| Hydrochloric Acid SCHEMBL5315581 | 0.88 | TRPM8 (0.66) | TRPM8TSHRKDM4ERAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007080109-A1 | SUBSTITUDED BENZYLOXY-PHENYLMETHYLUREA DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2007-07-19 | — | — | WO | disclosed |
| WO-2007080109-A1 | SUBSTITUDED BENZYLOXY-PHENYLMETHYLUREA DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2007-07-19 | — | — | WO | disclosed |