Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTR5A | P47898 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.42 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5315896 | 0.96 | TRPM8 (0.60) | TRPM8TSHRRAB9AKMT2AHTT | |
| Trifluoroacetic Acid SCHEMBL5315884 | 0.93 | TRPM8 (0.53) | TRPM8TSHRRAB9AKMT2AGAA | |
| SCHEMBL5315853 | 0.88 | TRPM8 (0.57) | TRPM8TSHRRAB9AKMT2AGAA | |
| Trifluoroacetic Acid SCHEMBL5111885 | 0.88 | TRPM8 (0.52) | TRPM8TSHRRAB9AKMT2AHTT | |
| SCHEMBL5318568 | 0.86 | TSHR (0.51) | TRPM8TSHRRAB9AKMT2AHTT | |
| SCHEMBL14463942 | 0.86 | TRPM8 (0.73) | TRPM8TSHRRAB9AKMT2AMEN1 | |
| Trifluoroacetic Acid SCHEMBL5114908 | 0.84 | TRPM8 (0.59) | TRPM8TSHRRAB9AKMT2AHTT | |
| SCHEMBL5321993 | 0.83 | TRPM8 (0.67) | TRPM8TSHRRAB9AKMT2AMEN1 | |
| SCHEMBL14078195 | 0.83 | TRPM8 (0.56) | TRPM8TSHRRAB9AKMT2AHTT | |
| SCHEMBL14464512 | 0.82 | TRPM8 (0.52) | TRPM8TSHRRAB9AKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007080109-A1 | SUBSTITUDED BENZYLOXY-PHENYLMETHYLUREA DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2007-07-19 | — | — | WO | disclosed |