Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31511812 | 0.92 | TSHR (0.53) | TSHRRAB9ALOXL2CYP4F2CYP4A11 | |
| SCHEMBL4810894 | 0.85 | SMN1; SMN2 (0.57) | TSHRRAB9AHPGDALDH1A1POLB | |
| SCHEMBL16880833 | 0.85 | ALDH1A1 (0.57) | TSHRRAB9ALOXL2CYP4F2CYP4A11 | |
| SCHEMBL16880714 | 0.85 | CYP4A11 (0.52) | TSHRRAB9ALOXL2CYP4F2CYP4A11 | |
| SCHEMBL3201147 | 0.85 | ALDH1A1 (0.55) | TSHRRAB9ALOXL2CYP4F2CYP4A11 | |
| Diphenylsulfane SCHEMBL29164339 | 0.84 | TSHR (0.68) | TSHRRAB9AHPGDALDH1A1POLB | |
| SCHEMBL9315162 | 0.84 | CYP1A2 (0.60) | TSHRRAB9ALOXL2CYP4F2CYP4A11 | |
| SCHEMBL5887658 | 0.84 | TSHR (0.67) | TSHRRAB9AHPGDALDH1A1POLB | |
| SCHEMBL29571134 | 0.84 | CYP1A2 (0.60) | TSHRRAB9ALOXL2CYP4F2CYP4A11 | |
| SCHEMBL16881547 | 0.84 | LOXL2 (0.49) | TSHRRAB9ALOXL2CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007064869-A2 | CATALYSTS FOR ARYL SULFIDE SYNTHESIS AND METHOD OF PRODUCING ARYL SULFIDES | YALE UNIVERSITY (US) | 2007-06-07 | — | — | WO | disclosed |
| WO-2007064869-A2 | CATALYSTS FOR ARYL SULFIDE SYNTHESIS AND METHOD OF PRODUCING ARYL SULFIDES | YALE UNIVERSITY (US) | 2007-06-07 | — | — | WO | disclosed |