Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.54 |
| ▸ | HBB | P68871 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.48 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5707744 | 0.91 | ALDH1A1 (0.57) | MAPTL3MBTL1NPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8628578 | 0.85 | MAOB (0.59) | MAPTL3MBTL1NPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5549549 | 0.85 | SMN1; SMN2 (0.62) | MAPTL3MBTL1NPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL28301654 | 0.84 | MAOB (0.63) | MAPTL3MBTL1NPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5314648 | 0.84 | L3MBTL1 (0.63) | MAPTL3MBTL1NPSR1SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10362241 | 0.84 | MAOB (0.57) | MAPTL3MBTL1NPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL31120710 | 0.83 | L3MBTL1 (0.67) | MAPTL3MBTL1NPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL29865080 | 0.83 | SMN1; SMN2 (0.60) | MAPTL3MBTL1NPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL13400266 | 0.83 | L3MBTL1 (0.71) | MAPTL3MBTL1NPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL29866302 | 0.83 | L3MBTL1 (0.71) | MAPTL3MBTL1NPSR1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007071344-A2 | NOVEL COUPLING CONSTITUENTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-06-28 | — | — | WO | claimed |
| WO-2007071344-A2 | NOVEL COUPLING CONSTITUENTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-06-28 | — | — | WO | disclosed |
| WO-2007071344-A2 | NOVEL COUPLING CONSTITUENTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-06-28 | — | — | WO | disclosed |