Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 1/20 | 0.41 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.39 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | TSPO | P30536 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4630463 | 0.89 | LPAR1 (0.45) | LPAR1LPAR5FFAR1FFAR4MAOB | |
| SCHEMBL4630536 | 0.85 | LPAR1 (0.51) | LPAR1LPAR5FFAR1FFAR4MAOB | |
| SCHEMBL4629905 | 0.80 | LPAR1 (0.46) | LPAR1LPAR5ALDH1A1MAOBSCN9A | |
| SCHEMBL3996243 | 0.78 | TP53 (0.48) | LPAR1LPAR5MAOBTSPOMAPT | |
| Tert-Butylamine SCHEMBL5309305 | 0.77 | LPAR1 (0.49) | LPAR1LPAR5ALDH1A1MAOBSCN9A | |
| Amantadine SCHEMBL5311412 | 0.76 | LPAR1 (0.42) | LPAR1LPAR5FFAR1FFAR4MAOB | |
| SCHEMBL4629897 | 0.76 | LPAR1 (0.53) | LPAR1LPAR5MAOBSCN9ASCN3A | |
| SCHEMBL4631178 | 0.76 | TSPO (0.53) | ALDH1A1TSPOMAPTKMT2AMEN1 | |
| SCHEMBL4764980 | 0.75 | FFAR4 (0.43) | FFAR1FFAR4MAOBMAPTPTPN1 | |
| SCHEMBL3997798 | 0.74 | TRPM8 (0.52) | LPAR1LPAR5MAOBTSPOMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007051995-A2 | TERT-BUTYLAMMONIUM SALT OR ADAMNTYLAMMONIUM SALT OF ORTHO-SUBSTITUTED BENZOIC ACID DERIVATIVES | ASTRAZENECA AB (SE) | 2007-05-10 | — | — | WO | disclosed |