SCHEMBL5316346

SCHEMBL5316346

CNC(CO)c1ccc(O)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.48
TAAR1 Q96RJ0 3/20 0.48
ALDH1A1 P00352 3/20 0.48
CYP2C9 P11712 2/20 0.48
HIF1A Q16665 2/20 0.48
KDM4E B2RXH2 2/20 0.48
HTR1A P08908 1/20 0.48
THPO P40225 1/20 0.48
BLM P54132 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
NMUR2 Q9GZQ4 1/20 0.48
ESR1 P03372 6/20 0.45
ALOX15 P16050 2/20 0.45
LMNA P02545 2/20 0.45
CYP1A2 P05177 1/20 0.45
PGR P06401 1/20 0.45
CHRM2 P08172 1/20 0.45
CYP3A4 P08684 1/20 0.45
ADORA3 P0DMS8 1/20 0.45
AR P10275 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4784533 0.98 TDP1 (0.47) TDP1TAAR1ALDH1A1CYP2C9HIF1A
SCHEMBL15787294 0.83 ALDH1A1 (0.43) TDP1ALDH1A1CYP2C9SMN1; SMN2LMNA
SCHEMBL15787619 0.83 ALDH1A1 (0.43) TDP1ALDH1A1CYP2C9SMN1; SMN2LMNA
SCHEMBL4538533 0.81 SLC6A4 (0.42) TDP1TAAR1HIF1AKDM4ESMN1; SMN2
SCHEMBL6646740 0.81 TRPA1 (0.41) TAAR1
SCHEMBL1978925 0.81 CYP1A2 (0.42) TAAR1ALDH1A1SMN1; SMN2CYP1A2SLC6A2
SCHEMBL6631545 0.81 ALDH1A1 (0.36) ALDH1A1ESR1ESR2TSHR
SCHEMBL1964723 0.80 ALDH1A1 (0.55) TAAR1ALDH1A1CYP2C9THPOALOX15
SCHEMBL1964722 0.80 ALDH1A1 (0.55) TAAR1ALDH1A1CYP2C9THPOALOX15
SCHEMBL4110424 0.80 ALDH1A1 (0.55) TAAR1ALDH1A1CYP2C9THPOALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007071683-A1 COMPOSITION FOR DYEING KERATIN FIBRES WITH A TETRAAZAPENTAMETHINE CATIONIC DIRECT DYE AND A NONIONIC SURFACTANT L'ORÉAL (FR) 2007-06-28 WO disclosed
WO-2004005407-A2 TETRA-AZAPENTAMETHINE AND USE THEREOF FOR DYEING KERATINOUS FIBERS L'OREAL (FR) 2004-01-15 WO disclosed