Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | C1R | P00736 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4481320 | 0.84 | MEN1 (0.53) | ALDH1A1HPGDMEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL4444966 | 0.82 | NSD2 (0.56) | ALDH1A1HPGDMEN1KMT2ALMNA | |
| SCHEMBL14415470 | 0.82 | HTR2A (0.51) | ALDH1A1HPGDKEAP1NFE2L2C1R | |
| SCHEMBL5316640 | 0.81 | KEAP1 (0.49) | ALDH1A1HPGDMEN1KMT2AKEAP1 | |
| SCHEMBL11888757 | 0.80 | KEAP1 (0.66) | ALDH1A1HPGDKEAP1NFE2L2POLB | |
| SCHEMBL15677745 | 0.80 | ALDH1A1 (0.59) | ALDH1A1HPGDMEN1KMT2ALMNA | |
| SCHEMBL10587159 | 0.79 | KMT2A (0.61) | ALDH1A1HPGDMEN1KMT2ALMNA | |
| SCHEMBL30639804 | 0.78 | NPY5R (0.50) | ALDH1A1HPGDKEAP1NFE2L2C1R | |
| SCHEMBL3248145 | 0.78 | CA1 (0.57) | ALDH1A1MEN1KMT2AKEAP1NFE2L2 | |
| SCHEMBL18537467 | 0.78 | CA1 (0.57) | MEN1KMT2AKEAP1NFE2L2C1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007067817-A1 | ABCA1 ELEVATING COMPOUNDS | CV THERAPEUTICS, INC. (US) | 2007-06-14 | — | — | WO | claimed |