Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL353412 | 0.83 | MAOA (0.51) | MEN1KMT2ATP53CYP1A2ADRB2 | |
| SCHEMBL18995758 | 0.82 | ALDH1A1 (0.60) | MEN1KMT2ATSHRALDH1A1HTT | |
| SCHEMBL62692 | 0.81 | HTT (0.64) | MEN1KMT2ATP53CYP1A2ADRB2 | |
| SCHEMBL62691 | 0.81 | HTT (0.64) | MEN1KMT2ATP53CYP1A2ADRB2 | |
| SCHEMBL19289840 | 0.81 | HTT (0.64) | MEN1KMT2ATP53CYP1A2ADRB2 | |
| SCHEMBL14969305 | 0.80 | ALDH1A1 (0.57) | MEN1KMT2ATSHRALDH1A1HTT | |
| SCHEMBL172569 | 0.80 | MAOA (0.59) | ALDH1A1MAOAMAOBBCHEADRA2B | |
| SCHEMBL7780082 | 0.80 | ALDH1A1 (0.54) | MEN1KMT2AALDH1A1HTTKDM4E | |
| SCHEMBL7786849 | 0.80 | ALDH1A1 (0.48) | MEN1KMT2ATP53CYP1A2ADRB2 | |
| SCHEMBL18995759 | 0.78 | ALDH1A1 (0.55) | MEN1KMT2ATSHRALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1565443-A4 | ACETYL 2-HYDROXY-1,3 DIAMINOALKANES | ELAN PHARM INC (US) | 2007-07-18 | — | — | EP | disclosed |
| EP-1565443-A2 | ACETYL 2-HYDROXY-1,3 DIAMINOALKANES | Elan Pharmaceuticals, Inc. (US) | 2005-08-24 | — | — | EP | disclosed |
| WO-2004024081-A2 | ACETYL 2-HYDROXY-1,3 DIAMINOALKANES | ELAN PHARMACEUTICALS, INC. (US) | 2004-03-25 | — | — | WO | disclosed |