Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14463969 | 0.88 | MTNR1A (0.41) | EGFRERBB2MTNR1AMTNR1BPOLB | |
| SCHEMBL5320827 | 0.84 | POLB (0.46) | EGFRERBB2MTNR1AMTNR1BGAA | |
| SCHEMBL5317248 | 0.83 | TSHR (0.46) | EGFRERBB2GAASMN1; SMN2TSHR | |
| SCHEMBL5316415 | 0.79 | TSHR (0.49) | EGFRERBB2MTNR1AMTNR1BGAA | |
| SCHEMBL5318568 | 0.77 | TSHR (0.51) | EGFRERBB2MTNR1AMTNR1BGAA | |
| SCHEMBL14464506 | 0.76 | TRPM8 (0.46) | MTNR1AMTNR1BGAAPOLBTSHR | |
| SCHEMBL14464060 | 0.75 | TRPM8 (0.49) | MTNR1AMTNR1BPOLBTSHRTDP1 | |
| SCHEMBL4091217 | 0.74 | SMN1; SMN2 (0.52) | GAASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL14464513 | 0.74 | TRPM8 (0.61) | GAAPOLBTSHRALDH1A1TDP1 | |
| SCHEMBL5321993 | 0.73 | TRPM8 (0.67) | MTNR1AMTNR1BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007080109-A1 | SUBSTITUDED BENZYLOXY-PHENYLMETHYLUREA DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2007-07-19 | — | — | WO | disclosed |