Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUSP3 | P51452 | 2/20 | 0.48 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL344681 | 0.83 | MAPT (0.48) | MAPTPTGDR2LMNAKDM4EHPGD | |
| SCHEMBL16962658 | 0.81 | L3MBTL1 (0.45) | DUSP3PTPN7MAPTL3MBTL1RAB9A | |
| SCHEMBL5204504 | 0.79 | CYP3A4 (0.39) | DUSP3PTPN7MAPTLMNAKDM4E | |
| SCHEMBL345774 | 0.78 | KDM4E (0.58) | PTGDR2KDM4EHPGDCFTRCYP2C19 | |
| SCHEMBL320173 | 0.78 | CYP2C19 (0.50) | MAPTKDM4EHPGDCFTRCYP2C19 | |
| SCHEMBL10577813 | 0.77 | ACHE (0.54) | MAPTL3MBTL1RAB9ALMNAKDM4E | |
| Hydrochloric Acid SCHEMBL10978991 | 0.77 | KDM4E (0.56) | PTGDR2KDM4EHPGDCFTRCYP2C19 | |
| SCHEMBL4638408 | 0.77 | CFTR (0.50) | MAPTL3MBTL1RAB9AKDM4EHPGD | |
| SCHEMBL29617695 | 0.77 | CFTR (0.50) | MAPTL3MBTL1RAB9AKDM4EHPGD | |
| SCHEMBL4070406 | 0.77 | CFTR (0.62) | MAPTLMNAKDM4EHPGDCFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539744-A4 | N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARM INC (US) | 2007-06-06 | — | — | EP | disclosed |
| EP-1539744-A2 | N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | Vicuron Pharmaceuticals, Inc. (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004007444-A2 | N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS, INC. (US) | 2004-01-22 | — | — | WO | disclosed |