Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.56 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | MPO | P05164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27455994 | 0.79 | TAAR1 (0.52) | TAAR1AOC3IDO1MPOMEN1 | |
| SCHEMBL12478612 | 0.78 | TAAR1 (0.56) | TAAR1AOC3IDO1MPOMAOB | |
| SCHEMBL2556909 | 0.78 | TAAR1 (0.56) | TAAR1AOC3IDO1MPODAO | |
| SCHEMBL29373563 | 0.78 | TAAR1 (0.56) | TAAR1AOC3IDO1MPODAO | |
| SCHEMBL28344566 | 0.78 | TAAR1 (0.56) | TAAR1AOC3IDO1MPOMAOB | |
| SCHEMBL7563209 | 0.78 | TAAR1 (0.56) | TAAR1AOC3IDO1MPOMAOB | |
| SCHEMBL8526001 | 0.78 | TAAR1 (0.75) | TAAR1AOC3IDO1MPOMAOB | |
| SCHEMBL5316677 | 0.77 | TAAR1 (0.48) | TAAR1AOC3IDO1MEN1KMT2A | |
| SCHEMBL9346870 | 0.76 | DAO (0.38) | TAAR1AOC3DAOHPGDSLC6A4 | |
| SCHEMBL2372931 | 0.76 | TAAR1 (0.56) | TAAR1KMT2ADAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160036-A | ADRENERGIC STIMULANTS | ALLEN & HANBURYS LIMITED (GB) | 1979-07-03 | — | — | US | claimed |
| EP-2595984-A1 | MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| EP-2595985-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| EP-2547665-A1 | INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2013-01-23 | — | — | EP | disclosed |
| WO-2012010568-A1 | MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |
| WO-2012010567-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |
| WO-2011113756-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-09-22 | — | — | WO | disclosed |
| CN-1119337-C | Substituted 2, 4-diamino-1, 3, 5-triazines as herbicides | BAYER AG (DE) | 2003-08-27 | — | — | CN | disclosed |
| CN-1239955-A | Substituted 2, 4-diamino-1, 3, 5-triazines as herbicides | BAYER AG (DE) | 1999-12-29 | — | — | CN | disclosed |
| CN-1239957-A | Substituting 2-amino-4-alkylamino-1,3,5-triazine as herbicide | BAYER AG (DE) | 1999-12-29 | — | — | CN | disclosed |
| EP-0934285-A1 | SUBSTITUTING 2-AMINO-4-ALKYLAMINO-1,3,5-TRIAZINE AS HERBICIDE | BAYER AG (DE) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998015539-A1 | SUBSTITUTING 2-AMINO-4-ALKYLAMINO-1,3,5-TRIAZINE AS HERBICIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1998-04-16 | — | — | WO | disclosed |
| EP-0355583-A2 | Cardiotonics | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-28 | — | — | EP | disclosed |
| US-4160036-A | ADRENERGIC STIMULANTS | ALLEN & HANBURYS LIMITED (GB) | 1979-07-03 | — | — | US | disclosed |