Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.43 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5316997 | 0.87 | KDM4E (0.50) | HPGDHDAC6HDAC1HDAC8HDAC3 | |
| SCHEMBL463732 | 0.80 | SMN1; SMN2 (0.53) | HCAR3HPGDHCAR2HDAC6SMN1; SMN2 | |
| SCHEMBL6320502 | 0.80 | HDAC6 (0.53) | HCAR3HPGDHCAR2HDAC6SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL440736 | 0.79 | SMN1; SMN2 (0.52) | HCAR3HPGDHCAR2HDAC6SMN1; SMN2 | |
| SCHEMBL5315622 | 0.77 | TLR9 (0.46) | — | |
| SCHEMBL12869558 | 0.75 | HCAR3 (0.47) | HCAR3HPGDHCAR2HDAC6SMN1; SMN2 | |
| SCHEMBL1144927 | 0.75 | HCAR3 (0.55) | HCAR3HPGDHCAR2HDAC6SMN1; SMN2 | |
| SCHEMBL554569 | 0.75 | HSD17B10 (0.64) | HCAR3SMN1; SMN2HSD17B10HTT | |
| SCHEMBL1970364 | 0.75 | HDAC6 (0.57) | HCAR3HPGDHDAC6HSD17B10HTT | |
| SCHEMBL5317666 | 0.75 | HDAC6 (0.52) | HCAR3HPGDHCAR2HDAC6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007069053-A1 | BENZIMIDAZOLE ANTAGONISTS OF THE H-3 RECEPTOR | PFIZER PRODUCTS INC. (US) | 2007-06-21 | — | — | WO | disclosed |