Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.46 |
| ▸ | IDH1 | O75874 | 4/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | ITK | Q08881 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5316684 | 0.87 | HCAR3 (0.50) | HDAC6EHMT2IDH1HPGDHDAC3 | |
| SCHEMBL408881 | 0.83 | KDM4E (0.53) | KDM4ENPC1LMNAMAPTRAB9A | |
| SCHEMBL4259457 | 0.80 | KDM4E (0.56) | KDM4ENPC1LMNAMAPTRAB9A | |
| SCHEMBL29989068 | 0.78 | RAB9A (0.72) | KDM4ENPC1LMNAMAPTRAB9A | |
| SCHEMBL31489 | 0.78 | RAB9A (0.72) | KDM4ENPC1LMNAMAPTRAB9A | |
| SCHEMBL28439988 | 0.77 | KDM4E (0.56) | KDM4ENPC1LMNAMAPTRAB9A | |
| SCHEMBL19029395 | 0.77 | KDM4E (0.56) | KDM4ENPC1LMNAMAPTRAB9A | |
| SCHEMBL30897550 | 0.77 | KDM4E (0.56) | KDM4ENPC1LMNAMAPTRAB9A | |
| SCHEMBL11947887 | 0.77 | KDM4E (0.56) | KDM4ENPC1LMNAMAPTRAB9A | |
| SCHEMBL5315571 | 0.76 | KDM4E (0.52) | KDM4ENPC1LMNAMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007069053-A1 | BENZIMIDAZOLE ANTAGONISTS OF THE H-3 RECEPTOR | PFIZER PRODUCTS INC. (US) | 2007-06-21 | — | — | WO | disclosed |