Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 10/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5309710 | 0.87 | ALDH1A1 (0.37) | LCKKDRMAPTALDH1A1KDM4E | |
| SCHEMBL5309927 | 0.85 | LCK (0.36) | LCKKDRIRAK4 | |
| SCHEMBL5316887 | 0.85 | LCK (0.38) | LCKKDRMAPTKDM4EIRAK4 | |
| SCHEMBL5310589 | 0.84 | LCK (0.38) | LCKNPC1KDRMAPTKDM4E | |
| SCHEMBL5314431 | 0.84 | LCK (0.35) | LCKKDRIRAK4 | |
| SCHEMBL5311529 | 0.84 | LCK (0.39) | LCKKDRMAPTALDH1A1L3MBTL1 | |
| SCHEMBL14530871 | 0.84 | LCK (0.39) | LCKKDRMAPTALDH1A1KDM4E | |
| SCHEMBL5312806 | 0.84 | LCK (0.39) | LCKNPC1LMNAMAPTALDH1A1 | |
| SCHEMBL5309870 | 0.84 | LCK (0.37) | LCKKDRMAPTKDM4EIRAK4 | |
| SCHEMBL14530637 | 0.84 | RAF1 (0.37) | LCKNPC1LMNAKDRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |