Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 7/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
| ▸ | GABRE | P78334 | 1/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.35 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.35 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5311529 | 0.93 | LCK (0.39) | LCKRXRARXRBIRAK4MAPT | |
| SCHEMBL5312036 | 0.91 | RXRA (0.39) | LCKSYKRXRARXRBIRAK4 | |
| SCHEMBL5312890 | 0.91 | LCK (0.38) | LCKIRAK4MEN1MAPTKMT2A | |
| SCHEMBL5310589 | 0.90 | LCK (0.38) | LCKRXRARXRBIRAK4MAPT | |
| SCHEMBL5313272 | 0.90 | LCK (0.38) | LCKSYKIRAK4MEN1MAPT | |
| SCHEMBL5316887 | 0.89 | LCK (0.38) | LCKIRAK4MAPTNR3C2KDM4E | |
| SCHEMBL5312746 | 0.88 | LCK (0.37) | LCKRXRARXRBIRAK4MAPT | |
| SCHEMBL5312732 | 0.88 | LCK (0.37) | LCKSYKIRAK4MEN1KMT2A | |
| SCHEMBL5311989 | 0.88 | LCK (0.37) | LCKIRAK4MEN1MAPTKMT2A | |
| SCHEMBL5312193 | 0.87 | ECE2 (0.42) | LCKIRAK4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |