Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.38 |
| ▸ | HPD | P32754 | 2/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | BMP1 | P13497 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | APLNR | P35414 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4816671 | 0.95 | AKR1B1 (0.42) | AKR1B1NAAAPYCR1HPDCHRM5 | |
| SCHEMBL15137118 | 0.80 | BMP1 (0.40) | AKR1B1PYCR1CHRM5BMP1NPC1 | |
| SCHEMBL5957680 | 0.80 | PTGER1 (0.41) | HPDPTGER1 | |
| SCHEMBL5673837 | 0.80 | PYCR1 (0.41) | PYCR1PTGER1MEN1KMT2A | |
| SCHEMBL1015757 | 0.78 | PYCR1 (0.40) | PYCR1MEN1KMT2A | |
| SCHEMBL14709471 | 0.78 | SMN1; SMN2 (0.36) | NPC1RAB9AKMT2A | |
| SCHEMBL26933279 | 0.76 | CA12 (0.32) | APLNR | |
| SCHEMBL2521711 | 0.76 | HTR2A (0.38) | PTGER1MEN1KMT2A | |
| SCHEMBL15414218 | 0.75 | PYCR1 (0.44) | PYCR1MEN1KMT2A | |
| SCHEMBL25330967 | 0.74 | MAPK14 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007069986-A1 | NEW OXABISPIDINE COMPOUNDS FOR THE TREATMENT OF CARDIAC ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2007-06-21 | — | — | WO | disclosed |