Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.39 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4180578 | 0.98 | NAAA (0.41) | NAAACHRM3CHRM2CHRM4CHRM1 | |
| SCHEMBL3913426 | 0.88 | CHRM1 (0.39) | NAAACHRM3CHRM2CHRM4CHRM1 | |
| Hydrochloric Acid SCHEMBL29429508 | 0.86 | CHRM1 (0.38) | NAAACHRM3CHRM2CHRM4CHRM1 | |
| Hydrochloric Acid SCHEMBL29429517 | 0.86 | CHRM1 (0.38) | NAAACHRM3CHRM2CHRM4CHRM1 | |
| SCHEMBL21765657 | 0.84 | NAAA (0.48) | NAAACHRM3CHRM2CHRM4CHRM1 | |
| SCHEMBL2253713 | 0.84 | — | — | |
| SCHEMBL3111263 | 0.84 | NAAA (0.51) | NAAAEPHX1GNAI3GNAO1GNAI1 | |
| SCHEMBL11377347 | 0.83 | NAAA (0.44) | NAAACHRM3POLBEPHX1GABRP | |
| Hydrochloric Acid SCHEMBL27604463 | 0.82 | NAAA (0.50) | NAAAGNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL22466294 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101627049-B | Synthesis of phthalamides | CARA THERAPEUTICS INC | 2012-09-05 | — | — | CN | claimed |
| CN-101627049-A | Synthesis of phthalamides | CARA THERAPEUTICS INC | 2010-01-13 | — | — | CN | claimed |
| CN-101535336-A | Synthetic phthalamides and dimers thereof | SYNTHETIC PEPTIDE AMIDES AND D (US) | 2009-09-16 | — | — | CN | claimed |
| US-3998827-A | HYPOTENSIVE AGENTS | THE UPJOHN COMPANY (US) | 1976-12-21 | — | — | US | claimed |
| CN-111788191-B | 1- (Piperidinylcarbonylmethyl) -2-oxopiperazine derivatives for the treatment of cancer | 英夕亚生物科技股份公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-110214012-A | Azole pyrimidines for the treatment of cancer-related diseases | 艾库斯生物科学有限公司 | 2019-09-06 | — | — | CN | disclosed |
| CN-108456204-A | Benzothiazine derivative and its preparation method and application | 四川大学 | 2018-08-28 | — | — | CN | disclosed |
| EP-2879673-A1 | COMPOUNDS THAT ARE S1P MODULATING AGENTS AND/OR ATX MODULATING AGENTS | Biogen Idec MA Inc. (US) | 2015-06-10 | — | — | EP | disclosed |
| CN-101535336-B | Synthetic phthalamides and dimers thereof | CARA THERAPEUTICS INC | 2014-04-02 | — | — | CN | disclosed |
| WO-2014025709-A1 | COMPOUNDS THAT ARE S1P MODULATING AGENTS AND/OR ATX MODULATING AGENTS | BIOGEN IDEC MA INC. (US) | 2014-02-13 | — | — | WO | disclosed |
| CN-101627049-B | Synthesis of phthalamides | CARA THERAPEUTICS INC | 2012-09-05 | — | — | CN | disclosed |
| CN-101801954-A | Compounds and compositions as modulators of GPR119 activity | IRM LLC | 2010-08-11 | — | — | CN | disclosed |
| EP-1305048-A2 | INHIBITORS OF CELLULAR EFFLUX PUMPS OF MICROBES | Wockhardt Limited (IN) | 2003-05-02 | — | — | EP | disclosed |
| US-20020177559-A1 | Quinolone derivatives | WOCKHARDT LIMITED | 2002-11-28 | — | — | US | disclosed |
| WO-2002009758-A2 | INHIBITORS OF CELLULAR EFFLUX PUMPS OF MICROBES | WOCKHARDT LIMITED (IN) | 2002-02-07 | — | — | WO | disclosed |
| CN-1314345-A | Novel piperidine-4-sulfamide compound, its preparing method and medicinal composition containing them | ADIR (FR) | 2001-09-26 | — | — | CN | disclosed |
| US-5661148-A | ANTIHYPOXIC AGENT FOR RESPIRATORY SYSTEM DISORDER | TEIJIN LIMITED (JP) | 1997-08-26 | — | — | US | disclosed |
| EP-0514540-B1 | PYRROLO 2,3-d]PYRIMIDINE DERIVATIVE, PROCESS FOR PREPARING THE SAME, AND PHARMACEUTICAL PREPARATION COMPRISING THE DERIVATIVE AS ACTIVE INGREDIENT | TEIJIN LTD (JP) | 1996-07-17 | — | — | EP | disclosed |
| EP-0514540-A1 | PYRROLO 2,3-d]PYRIMIDINE DERIVATIVE, PROCESS FOR PREPARING THE SAME, AND PHARMACEUTICAL PREPARATION COMPRISING THE DERIVATIVE AS ACTIVE INGREDIENT | TEIJIN LIMITED (JP) | 1992-11-25 | — | — | EP | disclosed |
| US-3998827-A | HYPOTENSIVE AGENTS | THE UPJOHN COMPANY (US) | 1976-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020177559-A1 | Quinolone derivatives | ABCB11, ABCB1, ABCG2 | NAAA 588/4885CHRM3 4041/4885CHRM2 4526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.