Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5334067 | 0.79 | KDM4E (0.56) | KMT2AMEN1KDM4EMAPTGAA | |
| SCHEMBL2464288 | 0.79 | KMT2A (0.50) | KMT2AMEN1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL5322990 | 0.77 | SMN1; SMN2 (0.50) | KMT2AMEN1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL29064573 | 0.77 | HTT (0.49) | KMT2AMEN1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL30749441 | 0.75 | GAA (0.41) | KMT2AMEN1KDM4EMAPTGAA | |
| SCHEMBL5322772 | 0.75 | KDM4E (0.54) | KMT2AMEN1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL2566401 | 0.75 | KMT2A (0.47) | KMT2AMEN1SMN1; SMN2KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL3768593 | 0.73 | MEN1 (0.46) | KMT2AMEN1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL11824328 | 0.73 | TSHR (0.55) | KMT2AMEN1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL2492070 | 0.73 | KDM4E (0.53) | KMT2AMEN1SMN1; SMN2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007079173-A2 | NOVEL 2-HETEROARYLOXY-PHENOL DERIVATIVES AS ANTIBACTERIAL AGENTS | EMERGENT BIOSOLUTIONS INC. (US) | 2007-07-12 | — | — | WO | disclosed |