Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5323868 | 0.81 | LMNA (0.55) | KDM4EMAPTKMT2ALMNAGAA | |
| SCHEMBL4366241 | 0.75 | LMNA (0.66) | KMT2ALMNAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL2464288 | 0.75 | KMT2A (0.50) | KDM4EMAPTKMT2ALMNAGAA | |
| SCHEMBL5317072 | 0.75 | KMT2A (0.50) | KDM4EMAPTKMT2ALMNAGAA | |
| SCHEMBL4434944 | 0.74 | LMNA (0.75) | KDM4EMAPTKMT2ALMNAGAA | |
| SCHEMBL9275219 | 0.74 | LMNA (0.58) | KDM4EMAPTKMT2ALMNAGAA | |
| SCHEMBL29064573 | 0.73 | HTT (0.49) | KDM4EMAPTKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL21858405 | 0.73 | HTT (0.60) | KDM4EMAPTKMT2ALMNAGAA | |
| SCHEMBL2540885 | 0.73 | LMNA (0.72) | MAPTKMT2ALMNAGAAALDH1A1 | |
| SCHEMBL31599172 | 0.72 | LMNA (0.72) | KDM4EMAPTKMT2ALMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007095495-A2 | BENZODIAZEPINE GCNF MODULATORS FOR STEM CELL MODULATION | PHARMACOPEIA, INC. (US) | 2007-08-23 | — | — | WO | disclosed |