Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11830034 | 0.88 | TSHR (0.44) | TSHRKDM4EALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL11128036 | 0.84 | KDM4E (0.47) | TSHRKDM4EALDH1A1SMN1; SMN2HDAC3 | |
| SCHEMBL29064573 | 0.75 | HTT (0.49) | TSHRKDM4EALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL5317072 | 0.73 | KMT2A (0.50) | TSHRKDM4EALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL29757946 | 0.72 | ADRA2C (0.71) | TSHRALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL3826083 | 0.72 | ADRA2C (0.71) | TSHRALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL10577713 | 0.71 | CYP1A2 (0.48) | KDM4EALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL2464288 | 0.70 | KMT2A (0.50) | TSHRKDM4EALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL2566401 | 0.70 | KMT2A (0.47) | KDM4EKMT2ASMN1; SMN2MEN1MAPT | |
| SCHEMBL5322772 | 0.70 | KDM4E (0.54) | KDM4EALDH1A1KMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3940392-A | Certain pyrazinyloxyphenyl urea compound | THE DOW CHEMICAL COMPANY (US) | 1976-02-24 | — | — | US | disclosed |