Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.69 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ACACB | O00763 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28622517 | 0.88 | LDHA (0.67) | LDHAPPARGPPARASLC6A4NPC1 | |
| SCHEMBL6576876 | 0.85 | KMT2A (0.56) | LDHAPPARGPPARANPC1POLB | |
| SCHEMBL19754023 | 0.85 | LDHA (0.57) | LDHASLC6A4SMN1; SMN2KMT2AACACB | |
| SCHEMBL19754035 | 0.83 | LDHA (0.56) | LDHAPPARGPPARASLC6A4KMT2A | |
| SCHEMBL27535176 | 0.83 | LDHA (0.59) | LDHAPPARGPPARAKMT2A | |
| SCHEMBL8283100 | 0.82 | LDHA (0.73) | LDHAPPARGPPARASLC6A4ACACB | |
| SCHEMBL663059 | 0.82 | LDHA (0.73) | LDHAPPARGPPARASLC6A4ACACB | |
| SCHEMBL490716 | 0.82 | LDHA (1.00) | LDHAPPARGPPARASLC6A4 | |
| SCHEMBL15592509 | 0.81 | LDHA (0.45) | LDHAPPARGPPARASMN1; SMN2CA1 | |
| SCHEMBL4990742 | 0.81 | LDHA (0.61) | LDHAPPARGPPARASLC6A4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3730502-A1 | SYNTHESIS AND APPLICATION OF OXASPIROCYCLODIPHOSPHINE LIGAND | SHENZHEN CATALYS TECHNOLOGY CO., LTD. (CN) | 2020-10-28 | — | — | EP | disclosed |
| WO-2019153203-A1 | SYNTHESIS AND APPLICATION OF OXASPIROCYCLODIPHOSPHINE LIGAND | 凯特立斯（深圳）科技有限公司 | 2019-08-15 | — | — | WO | disclosed |
| EP-1838654-A1 | PROCESS FOR THE MANUFACTURE OF SUBSTITUTED PROPIONIC ACIDS | Phoenix Chemicals Limited (GB) | 2007-10-03 | — | — | EP | disclosed |
| WO-2006075177-A1 | PROCESS FOR THE MANUFACTURE OF SUBSTITUTED PROPIONIC ACIDS | PHOENIX CHEMICALS LTD. (GB) | 2006-07-20 | — | — | WO | disclosed |