Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrothiophene SCHEMBL11662494 | 0.81 | — | — | |
| Cyclohexane SCHEMBL27620246 | 0.80 | EPHX1 (0.43) | EPHX1LMNACA12CA1CA2 | |
| Tetrahydrothiophene SCHEMBL5851736 | 0.80 | — | — | |
| Tetrahydrothiophene SCHEMBL1772563 | 0.77 | — | — | |
| Tetrahydrothiophene SCHEMBL1772562 | 0.77 | — | — | |
| Isobutyramide SCHEMBL11109750 | 0.76 | LMNA (0.46) | EPHX1LMNACA1CA2 | |
| Isobutyramide SCHEMBL3323 | 0.76 | — | — | |
| Tetrahydrothiophene SCHEMBL9620648 | 0.74 | — | — | |
| Tetrahydrothiophene SCHEMBL11325523 | 0.74 | — | — | |
| Isobutyramide SCHEMBL2402176 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007074391-A2 | PREPARATION OF A KEY INTERMEDIATE IN THE SYNTHESIS OF ROSUVASTATIN | KHAMAR BAKULESH MAFATLAL (IN) | 2007-07-05 | — | — | WO | claimed |
| WO-2007074391-A2 | PREPARATION OF A KEY INTERMEDIATE IN THE SYNTHESIS OF ROSUVASTATIN | KHAMAR BAKULESH MAFATLAL (IN) | 2007-07-05 | — | — | WO | disclosed |