Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL973327 | 0.86 | KDM2B (0.55) | MEN1KMT2AKDM2BPOLBTSHR | |
| SCHEMBL972842 | 0.85 | KDM2B (0.51) | MEN1KMT2AKDM2BPOLBTSHR | |
| SCHEMBL972843 | 0.85 | KDM2B (0.51) | MEN1KMT2AKDM2BPOLBTSHR | |
| SCHEMBL4972119 | 0.80 | HRH2 (0.47) | MEN1KMT2AKDM2BPOLBTSHR | |
| SCHEMBL4972565 | 0.79 | POLB (0.48) | MEN1KMT2AKDM2BPOLBTSHR | |
| SCHEMBL5604174 | 0.74 | POLB (0.43) | MEN1KMT2AKDM2BPOLBTSHR | |
| SCHEMBL2357857 | 0.73 | SMN1; SMN2 (0.49) | MEN1KMT2APOLBALDH1A1MAPT | |
| SCHEMBL5495665 | 0.73 | SMN1; SMN2 (0.49) | MEN1KMT2APOLBALDH1A1MAPT | |
| SCHEMBL8303596 | 0.73 | SMN1; SMN2 (0.49) | MEN1KMT2APOLBALDH1A1MAPT | |
| SCHEMBL1860263 | 0.73 | POLB (0.52) | MEN1KMT2AKDM2BPOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007117557-A2 | DIAMINOPROPANOL RENIN INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2007-10-18 | — | — | WO | disclosed |