Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.73 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.55 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6445182 | 0.90 | HSD17B10 (0.59) | HSD17B10PTGER4KMT2AMEN1POLB | |
| SCHEMBL4256918 | 0.87 | THRB (0.77) | HSD17B10PTGER4HTTTHRBKMT2A | |
| SCHEMBL22371434 | 0.86 | HSD17B10 (0.65) | HSD17B10PTGER4HTTTHRBKMT2A | |
| SCHEMBL120600 | 0.85 | HSD17B10 (1.00) | HSD17B10PTGER4HTTTHRBKMT2A | |
| SCHEMBL29784251 | 0.85 | HSD17B10 (1.00) | HSD17B10PTGER4HTTTHRBKMT2A | |
| SCHEMBL25112562 | 0.81 | PDE10A (0.63) | SIRT2SIRT1ALDH1A1FGFR1 | |
| SCHEMBL2696717 | 0.81 | HSD17B10 (0.58) | HSD17B10PTGER4HTTTHRBSMN1; SMN2 | |
| SCHEMBL22160864 | 0.80 | HSD17B10 (0.51) | HSD17B10PTGER4HTTTHRBKMT2A | |
| SCHEMBL3950784 | 0.80 | TP53 (0.50) | HSD17B10PTGER4HTTKMT2AMEN1 | |
| SCHEMBL1356520 | 0.80 | HSD17B10 (0.48) | HSD17B10PTGER4THRBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007069053-A1 | BENZIMIDAZOLE ANTAGONISTS OF THE H-3 RECEPTOR | PFIZER PRODUCTS INC. (US) | 2007-06-21 | — | — | WO | disclosed |