Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5430646 | 0.83 | KCNH2 (0.38) | KCNH2MCHR1SLC2A1ALDH1A1L3MBTL1 | |
| SCHEMBL5430642 | 0.83 | KCNH2 (0.38) | KCNH2MCHR1SLC2A1ALDH1A1L3MBTL1 | |
| SCHEMBL3697142 | 0.76 | SLC2A1 (0.47) | KCNH2SLC2A1ALDH1A1 | |
| SCHEMBL3697147 | 0.76 | SLC2A1 (0.47) | KCNH2SLC2A1ALDH1A1 | |
| SCHEMBL5317247 | 0.74 | MTNR1A (0.36) | KCNH2MCHR1SLC2A1ALDH1A1L3MBTL1 | |
| SCHEMBL5317252 | 0.74 | MTNR1A (0.36) | KCNH2MCHR1SLC2A1ALDH1A1L3MBTL1 | |
| SCHEMBL5728191 | 0.69 | KCNH2 (0.61) | KCNH2MCHR1SLC2A1HTR2AHTR2C | |
| SCHEMBL5441471 | 0.68 | KCNH2 (0.40) | KCNH2MCHR1SLC2A1ALDH1A1L3MBTL1 | |
| SCHEMBL5441479 | 0.68 | KCNH2 (0.40) | KCNH2MCHR1SLC2A1ALDH1A1L3MBTL1 | |
| SCHEMBL3769333 | 0.68 | KCNH2 (0.48) | KCNH2MCHR1SLC2A1HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781650-A1 | NOVEL COMPOUNDS HAVING AN ANTI-BACTERIAL ACTIVITY | Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006021448-A1 | NOVEL COMPOUNDS HAVING AN ANTI-BACTERIAL ACTIVITY | Morphochem Aktiengesellschaft für kombinatorische Chemie (DE) | 2006-03-02 | — | — | WO | disclosed |