Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5430642 | 1.00 | KCNH2 (0.38) | KCNH2ALDH1A1L3MBTL1SLC2A1SIGMAR1 | |
| SCHEMBL3697142 | 0.85 | SLC2A1 (0.47) | KCNH2ALDH1A1SLC2A1 | |
| SCHEMBL3697147 | 0.85 | SLC2A1 (0.47) | KCNH2ALDH1A1SLC2A1 | |
| SCHEMBL5317252 | 0.84 | MTNR1A (0.36) | KCNH2ALDH1A1L3MBTL1SLC2A1SIGMAR1 | |
| SCHEMBL5317247 | 0.84 | MTNR1A (0.36) | KCNH2ALDH1A1L3MBTL1SLC2A1SIGMAR1 | |
| SCHEMBL5317431 | 0.83 | KCNH2 (0.41) | KCNH2ALDH1A1L3MBTL1SLC2A1SIGMAR1 | |
| SCHEMBL5432729 | 0.80 | KCNH2 (0.39) | KCNH2ALDH1A1SLC2A1SIGMAR1SLC18A3 | |
| SCHEMBL5316423 | 0.79 | MCHR1 (0.45) | KCNH2SLC2A1MCHR1 | |
| SCHEMBL5430572 | 0.79 | KCNH2 (0.46) | KCNH2SLC2A1 | |
| SCHEMBL5441471 | 0.79 | KCNH2 (0.40) | KCNH2ALDH1A1L3MBTL1SLC2A1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070244103-A1 | Novel Compounds Having an Anti-Bacterial Activity | MORPHOCHEM AKTIENGESELLSCHAFT FUR KOMBINATORISCHE CHEMIE (DE) | 2007-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244103-A1 | Novel Compounds Having an Anti-Bacterial Activity | TOP1, TOP2A, TOP2B | KCNH2 3363/4885ALDH1A1 3625/4885L3MBTL1 822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.