Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | P2RY12 | Q9H244 | 14/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4005299 | 0.89 | ALDH1A1 (0.70) | ALDH1A1P2RY12KDM4ELMNAHPGD | |
| SCHEMBL30999840 | 0.85 | ALDH1A1 (0.76) | ALDH1A1P2RY12KDM4ELMNAHPGD | |
| SCHEMBL3874439 | 0.85 | ALDH1A1 (0.76) | ALDH1A1P2RY12KDM4ELMNAHPGD | |
| Hydrochloric Acid SCHEMBL4878714 | 0.84 | ALDH1A1 (0.74) | ALDH1A1P2RY12KDM4ELMNAHPGD | |
| SCHEMBL14598715 | 0.77 | ALDH1A1 (0.69) | ALDH1A1P2RY12KDM4ELMNAHPGD | |
| SCHEMBL719802 | 0.76 | TDP1 (0.50) | ALDH1A1P2RY12KDM4EHPGDTDP1 | |
| SCHEMBL4295294 | 0.74 | ALDH1A1 (0.73) | ALDH1A1P2RY12KDM4ELMNAHPGD | |
| SCHEMBL3926740 | 0.73 | ALDH1A1 (1.00) | ALDH1A1P2RY12KDM4E | |
| SCHEMBL30999844 | 0.73 | ALDH1A1 (1.00) | ALDH1A1P2RY12KDM4E | |
| SCHEMBL5611396 | 0.73 | ALDH1A1 (0.58) | ALDH1A1P2RY12KDM4ELMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836189-A1 | NOVEL PYRIDINE COMPOUNDS | AstraZeneca AB (SE) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006073361-A9 | NOVEL PYRIDINE COMPOUNDS | ASTRAZENECA AB (SE) | 2007-08-02 | — | — | WO | disclosed |
| WO-2006073361-A1 | NOVEL PYRIDINE COMPOUNDS | ASTRAZENECA AB (SE) | 2006-07-13 | — | — | WO | disclosed |