Methoxymethane

Methoxymethane

SCHEMBL5317705

CC(=O)Oc1ccc(NCCOc2ccc(Cl)cc2)cc1C(=O)O.COC

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.45
MAPT P10636 4/20 0.45
MEN1 O00255 3/20 0.45
LMNA P02545 2/20 0.45
POLB P06746 1/20 0.45
CFD P00746 2/20 0.44
NPC1 O15118 2/20 0.43
HPGD P15428 1/20 0.42
AKR1C3 P42330 1/20 0.42
AKR1C2 P52895 1/20 0.42
KDM4E B2RXH2 1/20 0.40
PNLIP P16233 1/20 0.40
GAA P10253 1/20 0.40
PPARA Q07869 1/20 0.40
HRH3 Q9Y5N1 1/20 0.40
ATM Q13315 1/20 0.39
RXFP1 Q9HBX9 1/20 0.39
ALDH1A1 P00352 1/20 0.39
TAAR1 Q96RJ0 1/20 0.39
DRD4 P21917 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5316326 0.98 CFD (0.46) KMT2AMAPTMEN1LMNAPOLB
Methoxymethane SCHEMBL5316071 0.97 KMT2A (0.46) KMT2AMAPTMEN1LMNAPOLB
Methoxymethane SCHEMBL5317742 0.91 CFD (0.46) KMT2AMAPTMEN1LMNACFD
Methoxymethane SCHEMBL5317331 0.90 PPARA (0.47) KMT2AMAPTMEN1CFDNPC1
SCHEMBL5317703 0.90 KMT2A (0.44) KMT2AMAPTMEN1LMNANPC1
Methoxymethane SCHEMBL5319099 0.90 CFD (0.45) KMT2AMAPTMEN1LMNAPOLB
SCHEMBL4308419 0.89 KMT2A (0.42) KMT2AMAPTMEN1LMNAPOLB
Methoxymethane SCHEMBL5317339 0.88 MRGPRX4 (0.49) KMT2AMAPTMEN1CFDNPC1
Methoxymethane SCHEMBL5321026 0.87 KDM4E (0.49) KMT2AMAPTMEN1LMNACFD
Methoxymethane SCHEMBL5321426 0.87 KMT2A (0.49) KMT2AMAPTMEN1LMNACFD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007119984-A1 SALICYLIC ACID DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING THEM NEUROTECH CO., LTD. (KR) 2007-10-25 WO disclosed