Methoxymethane

Methoxymethane

SCHEMBL5317339

CC(=O)Oc1ccc(NCCOc2ccc(Cl)cc2Cl)cc1C(=O)O.COC

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 7/20 0.49
MAPT P10636 3/20 0.48
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
S1PR4 O95977 1/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
KDM4E B2RXH2 3/20 0.44
TSHR P16473 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
CFD P00746 2/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C19 P33261 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methoxymethane SCHEMBL5321426 0.91 KMT2A (0.49) MRGPRX4MAPTMEN1KMT2AKDM4E
SCHEMBL5317336 0.90 S1PR4 (0.51) MRGPRX4MAPTNPC1RAB9AS1PR4
SCHEMBL4305586 0.89 MRGPRX4 (0.47) MRGPRX4MAPTNPC1RAB9AS1PR4
Methoxymethane SCHEMBL5317705 0.88 KMT2A (0.45) MAPTNPC1MEN1KMT2AKDM4E
SCHEMBL5316326 0.86 CFD (0.46) MAPTNPC1MEN1KMT2AKDM4E
Methoxymethane SCHEMBL5316071 0.85 KMT2A (0.46) MAPTNPC1MEN1KMT2AKDM4E
Methoxymethane SCHEMBL5317367 0.84 CFD (0.43) MRGPRX4MAPTNPC1RAB9AMEN1
SCHEMBL3417018 0.83 MAPT (0.51) MRGPRX4MAPTNPC1RAB9AKDM4E
Methoxymethane SCHEMBL5320997 0.83 MEN1 (0.65) MAPTRAB9AMEN1KMT2AKDM4E
Methoxymethane SCHEMBL5317742 0.81 CFD (0.46) MAPTNPC1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007119984-A1 SALICYLIC ACID DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING THEM NEUROTECH CO., LTD. (KR) 2007-10-25 WO disclosed