Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5321473 | 0.86 | HSPB1 (0.49) | KMT2AL3MBTL1MEN1POLBTSHR | |
| SCHEMBL30073074 | 0.84 | MEN1 (0.49) | KMT2AL3MBTL1MEN1POLBTSHR | |
| SCHEMBL18956866 | 0.84 | MEN1 (0.49) | KMT2AL3MBTL1MEN1POLBTSHR | |
| SCHEMBL5606789 | 0.81 | HSPB1 (0.52) | KMT2AMEN1ALDH1A1GAALMNA | |
| SCHEMBL2538774 | 0.81 | TSHR (0.52) | KMT2AL3MBTL1MEN1POLBTSHR | |
| SCHEMBL20240569 | 0.78 | TSHR (0.49) | KMT2AL3MBTL1MEN1POLBTSHR | |
| SCHEMBL30970189 | 0.77 | MAPT (0.52) | KMT2AL3MBTL1MEN1POLBTSHR | |
| SCHEMBL2539419 | 0.77 | MAPT (0.56) | KMT2AL3MBTL1MEN1POLBTSHR | |
| SCHEMBL2535336 | 0.77 | HSD17B10 (0.53) | KMT2AL3MBTL1MEN1POLBTSHR | |
| SCHEMBL14363505 | 0.75 | ALDH1A1 (0.55) | KMT2AL3MBTL1MEN1POLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007079173-A2 | NOVEL 2-HETEROARYLOXY-PHENOL DERIVATIVES AS ANTIBACTERIAL AGENTS | EMERGENT BIOSOLUTIONS INC. (US) | 2007-07-12 | — | — | WO | disclosed |