SCHEMBL5317934

SCHEMBL5317934

Nn1cncc1CO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27984196 0.76 GABRA5 (0.37)
SCHEMBL27782412 0.73
SCHEMBL19223362 0.73 CYP11B1 (0.38)
SCHEMBL15153529 0.71 SLC1A3 (0.53)
SCHEMBL860093 0.69 CYP11B2 (0.36)
SCHEMBL22236496 0.69 CYP11B1 (0.36)
SCHEMBL5391398 0.67 CYP11B1 (0.45)
SCHEMBL6950271 0.66 CYP11B1 (0.44)
SCHEMBL3954746 0.66 CYP3A4 (0.35)
SCHEMBL5657526 0.63 CYP11B1 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137822-A1 MULTIVALENT IMMUNOCONJUGATES FOR TARGETED RADIOISOTOPE THERAPY ABDERA THERAPEUTICS INC (US) 2026-05-21 US disclosed
EP-4577250-A1 MULTIVALENT IMMUNOCONJUGATES FOR TARGETED RADIOISOTOPE THERAPY Abdera Therapeutics Inc. (US) 2025-07-02 EP disclosed
WO-2024044551-A1 MULTIVALENT IMMUNOCONJUGATES FOR TARGETED RADIOISOTOPE THERAPY Abdera Therapeutics Inc. (US) 2024-02-29 WO disclosed
EP-4288109-A1 IMMUNOSTIMULATORY COMPOUNDS AND CONJUGATES Seagen Inc. (US) 2023-12-13 EP disclosed
CN-110249050-A Without label coding library of compounds 南纳治疗有限公司 2019-09-17 CN disclosed
CN-110049780-A Isoquinolinebenzodiazepine (IQB) -1 (chloromethyl) -2, 3-dihydro-1H-benzo [ E ] indole (CBI) dimer 塞勒兰特治疗公司 2019-07-23 CN disclosed
CN-109963870-A ANTI-B7-H3 ANTIBODIES AND ANTIBODY DRUG CONJUGATES 艾伯维公司 2019-07-02 CN disclosed
CN-109641962-A anti-B7-H3 antibodies and antibody drug conjugates 艾伯维公司 2019-04-16 CN disclosed
CN-109563167-A ANTI-B7-H3 ANTIBODIES AND ANTIBODY DRUG CONJUGATES 艾伯维公司 2019-04-02 CN disclosed
CN-106459200-A Anti-EGFR antibodies and antibody drug conjugates 艾伯维公司 2017-02-22 CN disclosed
WO-2007062138-A2 METHODS AND COMPOSITIONS FOR TREATING DISEASES TARGETING HUMAN PROMININ-1(CD133) APPLERA CORPORATION (US) 2007-05-31 WO disclosed