SCHEMBL5318079

SCHEMBL5318079

Oc1ccccc1Oc1cncc(Cl)c1

nearest known ligand 0.52

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.43
POLB P06746 1/20 0.43
GAA P10253 1/20 0.43
P2RX4 Q99571 1/20 0.42
MAPT P10636 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11663615 0.80 CA1 (0.43) KMT2APOLBGAAMAPT
SCHEMBL4696071 0.80 GAA (0.49) KMT2AGAAP2RX4MAPT
SCHEMBL4348260 0.77 SLC6A4 (0.54) KMT2AMAPT
SCHEMBL11545406 0.77 LTA4H (0.48) KMT2AGAAMAPT
SCHEMBL14465793 0.76 LMNA (0.56) KMT2AGAAMAPT
SCHEMBL5158065 0.75 CHRM1 (0.58) P2RX4
SCHEMBL4336169 0.74 HTT (0.54) KMT2AMAPT
SCHEMBL4693866 0.74 HPGD (0.55) KMT2APOLBGAAMAPT
SCHEMBL5318974 0.74 LMNA (0.53)
SCHEMBL2034696 0.72 PPARG (0.50) GAAP2RX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007079173-A2 NOVEL 2-HETEROARYLOXY-PHENOL DERIVATIVES AS ANTIBACTERIAL AGENTS EMERGENT BIOSOLUTIONS INC. (US) 2007-07-12 WO claimed
WO-2007079173-A2 NOVEL 2-HETEROARYLOXY-PHENOL DERIVATIVES AS ANTIBACTERIAL AGENTS EMERGENT BIOSOLUTIONS INC. (US) 2007-07-12 WO disclosed
WO-2007079173-A2 NOVEL 2-HETEROARYLOXY-PHENOL DERIVATIVES AS ANTIBACTERIAL AGENTS EMERGENT BIOSOLUTIONS INC. (US) 2007-07-12 WO disclosed