Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 2/20 | 0.45 |
| ▸ | JUN | P05412 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | GUSB | P08236 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 4/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11837578 | 0.77 | MAPT (0.50) | NFKB1JUNNFE2L2CA4CA1 | |
| SCHEMBL11837572 | 0.77 | MAPT (0.50) | NFKB1JUNNFE2L2CA4CA1 | |
| SCHEMBL13857111 | 0.77 | MAOB (0.51) | NFKB1JUNNFE2L2CA4CA1 | |
| SCHEMBL11837318 | 0.76 | LMNA (0.67) | NFKB1JUNNFE2L2CA4CA1 | |
| SCHEMBL11837322 | 0.76 | LMNA (0.67) | NFKB1JUNNFE2L2CA4CA1 | |
| SCHEMBL19901101 | 0.74 | NFKB1 (0.59) | NFKB1JUNNFE2L2CA4CA1 | |
| SCHEMBL2391128 | 0.73 | MAPT (0.59) | NFKB1JUNNFE2L2CA4CA1 | |
| SCHEMBL3132306 | 0.73 | MAPT (0.59) | NFKB1JUNNFE2L2CA4CA1 | |
| SCHEMBL78103 | 0.72 | HCAR2 (0.53) | CA4LMNAAKR1B10AKR1B1CA12 | |
| SCHEMBL2340792 | 0.72 | HCAR2 (0.53) | CA4LMNAAKR1B10AKR1B1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1803809-A2 | Modulation of peroxisome proliferator-activated receptors | Abgenomics Corporation (TW) | 2007-07-04 | — | — | EP | disclosed |
| US-20070037193-A1 | Modulation of peroxisome proliferator-activated receptors | ABGENOMICS CORPORATION (TW) | 2007-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037193-A1 | Modulation of peroxisome proliferator-activated receptors | PPARG, PPARA, PPARD | NFKB1 1541/4885JUN 2187/4885NFE2L2 790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.