Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.92 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.53 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 3/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL250473 | 0.96 | TSHR (1.00) | TSHRLOXL2KCNJ1KCNH2ALDH1A1 | |
| SCHEMBL3887887 | 0.90 | TSHR (0.89) | TSHRLOXL2KCNJ1KCNH2ALDH1A1 | |
| SCHEMBL11364453 | 0.89 | TSHR (0.79) | TSHRLOXL2KCNJ1KCNH2ALDH1A1 | |
| SCHEMBL1449170 | 0.85 | TSHR (0.79) | TSHRKCNJ1KCNH2ALDH1A1IDO1 | |
| SCHEMBL378397 | 0.84 | TSHR (0.78) | TSHRLOXL2KCNJ1KCNH2ALDH1A1 | |
| SCHEMBL7569634 | 0.84 | TSHR (0.70) | TSHRLOXL2KCNJ1KCNH2ALDH1A1 | |
| SCHEMBL28771711 | 0.83 | TSHR (0.74) | TSHRKCNH2ALDH1A1 | |
| SCHEMBL9196397 | 0.83 | TSHR (0.74) | TSHRLOXL2KCNJ1KCNH2ALDH1A1 | |
| SCHEMBL3292782 | 0.83 | TSHR (0.75) | TSHRLOXL2KCNJ1KCNH2ALDH1A1 | |
| SCHEMBL358325 | 0.82 | TSHR (0.75) | TSHRLOXL2KCNJ1KCNH2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797055-A2 | PHOSPHATE ESTER FLAME RETRADANTS FROM RESORCINOL-KETONE REACTION PRODUCTS | INDSPEC CHEMICAL CORPORATION (US) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006036880-A2 | PHOSPHATE ESTER FLAME RETRADANTS FROM RESORCINOL-KETONE REACTION PRODUCTS | INDSPEC CHEMICAL CORPORATION (US) | 2006-04-06 | — | — | WO | disclosed |