Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.74 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | PTPRF | P10586 | 1/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 2/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL250473 | 0.86 | TSHR (1.00) | TSHRMEN1KMT2AHDAC6CYP2C19 | |
| Methyl Alcohol SCHEMBL5318262 | 0.83 | TSHR (0.92) | TSHRHDAC6CYP2C19ALDH1A1KCNJ1 | |
| Benzoic Acid SCHEMBL8816046 | 0.83 | TSHR (0.72) | TSHRMEN1KMT2AHDAC6SMN1; SMN2 | |
| SCHEMBL3887887 | 0.81 | TSHR (0.89) | TSHRMEN1KMT2AHDAC6CYP2C19 | |
| SCHEMBL9854491 | 0.80 | ALDH1A1 (0.65) | MEN1KMT2ACYP2C19CYP1A2NPC1 | |
| SCHEMBL15660584 | 0.80 | ALDH1A1 (0.65) | MEN1KMT2ACYP2C19CYP1A2NPC1 | |
| SCHEMBL11805023 | 0.80 | CYP1A2 (0.51) | TSHRMEN1KMT2ACYP2C19CYP1A2 | |
| SCHEMBL5973940 | 0.80 | CYP2C19 (0.51) | TSHRMEN1KMT2ACYP2C19CYP1A2 | |
| SCHEMBL13946243 | 0.79 | CYP1A2 (0.67) | TSHRMEN1KMT2ACYP2C19CYP1A2 | |
| SCHEMBL11364453 | 0.77 | TSHR (0.79) | TSHRMEN1KMT2AHDAC6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640091-A4 | SYNTHESIS OF NUCLEOTIDE MONOMERS. | RIBOZYME PHARM INC (US) | 1995-07-26 | — | — | EP | disclosed |
| EP-0640091-A1 | SYNTHESIS OF NUCLEOTIDE MONOMERS | RIBOZYME PHARMACEUTICALS, INC. (US) | 1995-03-01 | — | — | EP | disclosed |
| WO-1993023413-A1 | SYNTHESIS OF NUCLEOTIDE MONOMERS | RIBOZYME PHARMACEUTICALS, INC. (US) | 1993-11-25 | — | — | WO | disclosed |