Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5318284 | 1.00 | PPARG (0.41) | PPARGSLC22A12P2RX7ENPP2NR1H2 | |
| SCHEMBL4109252 | 0.92 | LMNA (0.43) | PPARGSLC22A12ENPP2LMNAMLYCD | |
| SCHEMBL997568 | 0.92 | LMNA (0.43) | PPARGSLC22A12ENPP2LMNAMLYCD | |
| SCHEMBL5319812 | 0.91 | KCNK3 (0.40) | SLC22A12ENPP2MLYCDALDH1A1PTGDR2 | |
| SCHEMBL5319814 | 0.91 | KCNK3 (0.40) | SLC22A12ENPP2MLYCDALDH1A1PTGDR2 | |
| SCHEMBL5321226 | 0.88 | ENPP2 (0.41) | PPARGSLC22A12ENPP2NR1H2NR1H3 | |
| SCHEMBL5321228 | 0.88 | ENPP2 (0.41) | PPARGSLC22A12ENPP2NR1H2NR1H3 | |
| SCHEMBL12693789 | 0.87 | ENPP2 (0.44) | PPARGSLC22A12P2RX7ENPP2NR1H2 | |
| SCHEMBL5323793 | 0.87 | ENPP2 (0.41) | PPARGSLC22A12ENPP2LMNAMLYCD | |
| SCHEMBL5323790 | 0.87 | ENPP2 (0.41) | PPARGSLC22A12ENPP2LMNAMLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786424-A2 | LONIDAMINE ANALOGUES AND THEIR USE IN MALE CONTRACEPTION AND CANCER TREATMENT | The University of Kansas (US) | 2007-05-23 | — | — | EP | claimed |
| WO-2006023704-A2 | LONIDAMINE ANALOGUES AND THEIR USE IN MALE CONTRACEPTION AND CANCER TREATMENT | UNIVERSITY OF KANSAS (US) | 2006-03-02 | — | — | WO | claimed |